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Merck

ROCK2

Rho-associated, coiled-coil containing protein kinase 2

Sinônimos:
ROCK-II
Espécies:
Human ROCK2 (9475), Mouse Rock2 (19878), Rat Rock2 (25537), chicken ROCK2 (374182), dog ROCK2 (482970), domestic cat ROCK2 (101094501), cow ROCK2 (282041), sheep ROCK2 (101103800), sheep ROCK2 (100294663), naked mole-rat Rock2 (101724195)
ID UniProtKB:
O75116, Q53QZ0, Q53SJ7, Q9UQN5
ID do gene:
  • Human(9475) Summary: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008]
  • Mouse(19878) Rho-associated coiled-coil containing protein kinase 2
  • Rat(25537) Rho-associated coiled-coil containing protein kinase 2
  • chicken(374182) Rho-associated, coiled-coil containing protein kinase 2
  • dog(482970) Rho-associated, coiled-coil containing protein kinase 2
  • domestic cat(101094501) Rho-associated, coiled-coil containing protein kinase 2
  • cow(282041) Rho-associated, coiled-coil containing protein kinase 2
  • sheep(101103800) Rho-associated, coiled-coil containing protein kinase 2
  • sheep(100294663) Rho-associated, coiled-coil containing protein kinase 2
  • naked mole-rat(101724195) Rho-associated, coiled-coil containing protein kinase 2
  • domestic guinea pig(100713798) Rho-associated, coiled-coil containing protein kinase 2

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
HPA007459
Anti-ROCK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
SAB4301564
Anti-phospho-ROCK2 (pTyr722) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
western blot
ZRB2155
Anti-ROCK2 Antibody, clone 1B20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
canine, feline, horse, human, monkey, mouse, rat
Aplicação
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
HPA044109
Anti-ROCK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
western blot
SAB5702825
Anti-ROCK2 Antibody, clone 8G3U2, Rabbit Monoclonal, ,
Reatividade de espécies
human, rat
Aplicação
immunohistochemistry
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Y0503
Y-27632, ≥98% (HPLC),
Espécies
human
A8626
Adenina, ≥99%,
Espécies
human, rat, mouse
A2786
Adenina, BioReagent, suitable for cell culture,
Espécies
human, rat, mouse
A5665
Adenina, BioReagent, suitable for plant cell culture, ≥99%,
Espécies
human, rat, mouse

Proteins

Número do produto
Descrição
Espécies
SRP5214
ROCK2 (5-554), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
EHU030131
MISSION® esiRNA, targeting human ROCK2,
Espécies
human