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Merck

PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

Sinônimos:
COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS
Espécies:
ID UniProtKB:
ID do gene:
  • Human(5742) Summary: This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
  • Mouse(19224) prostaglandin-endoperoxide synthase 1
  • Rat(24693) prostaglandin-endoperoxide synthase 1
  • Zebrafish(246226) prostaglandin-endoperoxide synthase 1
  • dog(403544) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • Horse(100034087) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic cat(101092557) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • chicken(427752) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic guinea pig(100714030) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • naked mole-rat(101698854) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • cow(282022) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • sheep(443551) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Anti-PTGS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-COX1 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
ELISA
immunohistochemistry

western blot
Anti-COX1/PTGS1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human, mouse
Aplicação
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-PTGS1 (AB1) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, guinea pig, horse, human, mouse, rat, sheep
Aplicação
immunohistochemistry
western blot
Anti-PTGS1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Antipyrine, analytical standard,
Espécies
human
Phenazone, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Diclofenac sodium salt, ,
Espécies
human
Naproxen sodium, 98.0-102.0%,
Espécies
human
Ibuprofen, ,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human PTGS1,
Espécies
human
MISSION® esiRNA, targeting mouse Ptgs1,
Espécies
mouse