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Merck

NDUFV1

NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa

Sinônimos:
CI-51K, CI51KD, UQOR1
Espécies:
ID UniProtKB:
ID do gene:
  • Human(4723) Summary: The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]
  • Mouse(17995) NADH dehydrogenase (ubiquinone) flavoprotein 1
  • Rat(293655) NADH dehydrogenase (ubiquinone) flavoprotein 1
  • Zebrafish(445291) NADH dehydrogenase (ubiquinone) flavoprotein 1
  • chicken(430210) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
  • dog(476004) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
  • cow(287014) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
  • domestic cat(101093395) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
  • sheep(101121129) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
  • naked mole-rat(101726275) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
  • domestic guinea pig(100725831) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-NDUFV1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Monoclonal Anti-NDUFV1 antibody produced in mouse, clone 4A7, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot
Anti-NDUFV1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
1,1-Dimethylbiguanide hydrochloride, 97%,
Espécies
human
Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Espécies
human
Metformin hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human NDUFV1,
Espécies
human
MISSION® esiRNA, targeting mouse Ndufv1,
Espécies
mouse