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Merck

MYC

v-myc avian myelocytomatosis viral oncogene homolog

Sinônimos:
MRTL, MYCC, bHLHe39, c-Myc
Espécies:
Human MYC (4609), Mouse Myc (17869), Rat Myc (24577), chicken MYC (420332), dog MYC (403924), domestic cat MYC (100379628), cow MYC (511077), domestic guinea pig Myc (100724557), Domestic Rabbit MYC (100327265), sheep MYC (443447)
ID UniProtKB:
P01106, A8WFE7, P01107, Q14026
ID do gene:
  • Human(4609) Summary: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17869) myelocytomatosis oncogene
  • Rat(24577) myelocytomatosis oncogene
  • chicken(420332) v-myc myelocytomatosis viral oncogene homolog
  • dog(403924) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic cat(100379628) v-myc myelocytomatosis viral oncogene homolog (avian)
  • cow(511077) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic guinea pig(100724557) v-myc myelocytomatosis viral oncogene homolog (avian)
  • Domestic Rabbit(100327265) v-myc myelocytomatosis viral oncogene homolog (avian)
  • sheep(443447) v-myc myelocytomatosis viral oncogene homolog (avian)

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ELISA

Número do produto
Descrição
Espécies
RAB1379
Human c-Myc ELISA, for serum, plasma and cell culture supernatants,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
SAB4702005
Monoclonal Anti-c-Myc tag Biotin produced in mouse, ,
Reatividade de espécies
Aplicação
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
M4439
Anti-c-Myc antibody, Mouse monoclonal, clone 9E10, purified from hybridoma cell culture,
Reatividade de espécies
human
Aplicação
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
05-724
Anticorpo anticauda Myc, clone 4A6, clone 4A6, Upstate®, from mouse,
Reatividade de espécies
human
Aplicação
ChIP
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
C3956
Anti-c-Myc antibody produced in rabbit, ~0.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
microarray
western blot
16-308
Anti-Myc Tag Antibody, clone 9E10, Alexa Fluor™ 488 conjugate, clone 9E10, Upstate®, from mouse,
Reatividade de espécies
all
Aplicação
immunocytochemistry
western blot

Proteins

Número do produto
Descrição
Espécies
SRP2089
C-myc, proto oncogene human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
EHU021051
MISSION® esiRNA, targeting human MYC,
Espécies
human
EMU075291
MISSION® esiRNA, targeting mouse Myc,
Espécies
mouse