CTLA4
cytotoxic T-lymphocyte-associated protein 4
Sinônimos:
CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12
Espécies:
Human CTLA4 (1493), Mouse Ctla4 (12477), Rat Ctla4 (63835), Domestic Rabbit CTLA4 (100009412), domestic guinea pig Ctla4 (100725760), naked mole-rat Ctla4 (101722788), chicken CTLA4 (424106), domestic cat CTLA4 (493743), cow CTLA4 (281732), dog CTLA4 (403696)
ID UniProtKB:
ID do gene:
- Human(1493) Summary: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
- Mouse(12477) cytotoxic T-lymphocyte-associated protein 4
- Rat(63835) cytotoxic T-lymphocyte-associated protein 4
- Domestic Rabbit(100009412) cytotoxic T-lymphocyte-associated protein 4
- domestic guinea pig(100725760) cytotoxic T-lymphocyte-associated protein 4
- naked mole-rat(101722788) cytotoxic T-lymphocyte-associated protein 4
- chicken(424106) cytotoxic T-lymphocyte-associated protein 4
- domestic cat(493743) cytotoxic T-lymphocyte-associated protein 4
- cow(281732) cytotoxic T-lymphocyte-associated protein 4
- dog(403696) cytotoxic T-lymphocyte-associated protein 4
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-CTLA4/CD152 Antibody, clone 1D10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human, monkey
Aplicação
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Anti-CD152 (CTLA-4) Antibody (mouse), APC, clone UC10-4F10-11, clone UC10-4F10-11, 0.2 mg/mL, from hamster(Armenian),
Reatividade de espécies
mouse
Aplicação
flow cytometry
Monoclonal Anti-CD152 antibody produced in mouse, ~1 mg/mL, clone AS32, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
neutralization
western blot
western blot
Monoclonal Anti-CTLA4 antibody produced in mouse, clone 2F1, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-CD152 (CTLA-4) (mouse), PE-Cy7, clone UC10-4F10-11 Antibody, clone UC10-4F10-11, from hamster(Armenian), PE-Cy7,
Reatividade de espécies
mouse
Aplicação
flow cytometry
Proteins
esiRNA
Número do produto
Descrição
Espécies