CASP9
caspase 9, apoptosis-related cysteine peptidase
Sinônimos:
APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56
Espécies:
Human CASP9 (842), Mouse Casp9 (12371), Rat Casp9 (58918), Zebrafish casp9 (492763), dog CASP9 (487432), Horse CASP9 (100054331), cow CASP9 (100140945), domestic cat CASP9 (768260), chicken CASP9 (426970), domestic guinea pig Casp9 (100714954) ...Mais
ID UniProtKB:
ID do gene:
- Human(842) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
- Mouse(12371) caspase 9
- Rat(58918) caspase 9, apoptosis-related cysteine peptidase
- Zebrafish(492763) caspase 9, apoptosis-related cysteine protease
- dog(487432) caspase 9, apoptosis-related cysteine peptidase
- Horse(100054331) caspase 9, apoptosis-related cysteine peptidase
- cow(100140945) caspase 9, apoptosis-related cysteine peptidase
- domestic cat(768260) caspase 9, apoptosis-related cysteine peptidase
- chicken(426970) caspase 9, apoptosis-related cysteine peptidase
- domestic guinea pig(100714954) caspase 9, apoptosis-related cysteine peptidase
- naked mole-rat(101702898) caspase 9, apoptosis-related cysteine peptidase
- sheep(101110953) caspase 9, apoptosis-related cysteine peptidase
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Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-CASP9 (Cleaved-Asp330), C-Terminal antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Caspase 9 antibody,Mouse monoclonal, clone CAS9, purified from hybridoma cell culture,
Reatividade de espécies
human
Aplicação
ELISA
microarray
western blot
microarray
western blot
Anti-Caspase 9 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
western blot
Anti-Caspase-9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Caspase 9 antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Kits
Número do produto
Descrição
Espécies
Kit de ensaio de atividade colorimétrica da caspase 9, LEHD, Caspase-9 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the LEHD.,
Espécies
human
Caspase 9 Colorimetric Activity Assay Kit, LEHD, Caspase-9 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the LEHD.,
Espécies
human
esiRNA
Small Molecule - Substrate
Número do produto
Descrição
Espécies
N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin, ≥95% (HPLC), powder,
Espécies
mouse, rat, human