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504270

Supelco

Tube de SPE Supelclean™ LC-18

bed wt. 100 mg, volume 1 mL, pk of 108

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About This Item

Code UNSPSC :
41115712

Matériaux

PE frit (20 μm porosity)
polypropylene hardware

Niveau de qualité

100

Gamme de produits

Supelclean™

Caractéristiques

endcapped

Composition

bed wt., 100 mg

Conditionnement

pk of 108

Ampleur du marquage

~11.5% C loading

Technique(s)

solid phase extraction (SPE): suitable

Superficie

475 m2/g

Volume

1 mL

Matrice

silica gel base material (irregularly shaped)

Groupe de la matrice active

C18 (octadecyl) bonding, monomerically bonded

Taille des particules

45 μm

Dimension de pores

0.8 cm3/g pore volume
60 Å pore size

Application(s)

food and beverages

Technique de séparation

reversed phase

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Description générale

Supelclean™ LC-18 SPE tube is used in solid phase extraction (SPE) method to extract non-polar to moderately polar compounds from aqueous samples.

Application

Supelclean™ LC-18 SPE Tube may be used for the solid-phase extraction of:
  • Artesunate, dihydroartemisinin, mefloquine, amodiaquine and desethylamodiaquine in human plasma samples prior to their determination by reversed phase high performance liquid chromatography (RP-HPLC) coupled to electrochemical (EC) detector or ultraviolet (UV) detector.
  • Ursodeoxycholic acid in blood serum samples prior to its analysis by HPLC-UV.
  • Calycosin-7-O-β-D-glucoside, ononin, astragaloside IV, astragaloside I and ferulic acid in rat plasma samples after oral administration of Danggui Buxue Tang extract, prior to their pharmacokinetic studies by LC coupled to mass spectrometry (MS).

Informations légales

Supelclean is a trademark of Sigma-Aldrich Co. LLC

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
16631401
14721101
14166301
13043801
12324801

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Consulter la Bibliothèque de documents

Validation of high performance liquid chromatography-electrochemical detection methods with simultaneous extraction procedure for the determination of artesunate, dihydroartemisinin, amodiaquine and desethylamodiaquine in human plasma for application in clinical pharmacological studies of artesunate-amodiaquine drug combination.
Lai CS, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 877(5-6), 558-562 (2009)
Simultaneous determination of calycosin-7-O-β-D-glucoside, ononin, astragaloside IV, astragaloside I and ferulic acid in rat plasma after oral administration of Danggui Buxue Tang extract for their pharmacokinetic studies by liquid chromatography-mass spectrometry.
Wen XD, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 865(1-2), 99-105 (2008)
An analytical method with a single extraction procedure and two separate high performance liquid chromatographic systems for the determination of artesunate, dihydroartemisinin and mefloquine in human plasma for application in clinical pharmacological studies of the drug combination.
Lai CS, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 857(2), 308-314 (2007)
Barbara Sivakova et al.
International journal of molecular sciences, 22(4) (2021-02-13)
The phosphorylation of proteins modulates various functions of proteins and plays an important role in the regulation of cell signaling. In recent years, label-free quantitative (LFQ) phosphoproteomics has become a powerful tool to analyze the phosphorylation of proteins within complex
M Nobilis et al.
Journal of pharmaceutical and biomedical analysis, 24(5-6), 937-946 (2001-03-15)
Ursodeoxycholic acid (3 alpha,7 beta-dihydroxy-5 beta-cholanoic acid, UDCA) is a therapeutically applicable bile acid widely used for the dissolution of cholesterol-rich gallstones and in the treatment of chronic liver diseases associated with cholestasis. UDCA is more hydrophilic and less toxic

Articles

Solid Phase Extraction: Reversed-Phase Methodology

Reversed-phase interaction will retain most molecules with hydrophobic character; it is very useful for extracting analytes that are very diverse in structure within the same sample.

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