444225

MMP-3 Inhibitor II

The MMP-3 Inhibitor II, also referenced under CAS 161314-17-6, controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• Synonyme(s) : MMP-3 Inhibitor II, N-Isobutyl-N-(4-methoxyphenylsulfonyl)-glycylhydroxamic Acid, NNGH
• Formule empirique (notation de Hill): C₁₃H₂₀N₂O₅S
• Numéro CAS: 161314-17-6
• Poids moléculaire : 316.37
• Numéro MDL: MFCD02179370
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥98% (TLC)
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze
• Couleur: white
• Solubilité: DMSO: 30 mg/mL; ethanol: 8 mg/mL
• Conditions d'expédition: ambient
• Température de stockage: 10-30°C

Description

Description générale

A cell-permeable, potent inhibitor of human MMP-3 (stromelysin; K_i = 130 nM).

A potent and cell-permeable inhibitor of human MMP-3 (K_i = 130 nM).

Actions biochimiques/physiologiques

Cell permeable: yes

Primary Target
human MMP-3

Product does not compete with ATP.

Reversible: no

Target K_i: 130 nM against human MMP-3

Avertissement

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Autres remarques

Kato, N., et al. 2002. Genome Informatics13, 272.
MacPherson, L.J., et al. 1997. J. Med. Chem. 40, 2525.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable