SMB00472

Palmatine chloride

≥98% (HPLC)

• Synonyme(s) : Berbinium, Dibenzo[a,g]quinolizinium,5,6-dihydro-2,3,9,10-tetramethoxychloride, Fibrauretin chloride
• Formule empirique (notation de Hill): C₂₁H₂₂ClNO₄
• Numéro CAS: 10605-02-4
• Poids moléculaire : 387.86
• Numéro MDL: MFCD00016656
• Code UNSPSC : 12352205
• ID de substance PubChem : 329825027
• Nomenclature NACRES : NA.25

Propriétés

• Niveau de qualité: 200
• Pureté: ≥98% (HPLC)
• Forme: powder
• Application(s): metabolomics; vitamins, nutraceuticals, and natural products
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Chaîne SMILES: COC1=CC2=C(C=C1OC)CC[N+]3=CC4=C(OC)C(OC)=CC=C4C=C32.[Cl-]
• InChI: 1S/C21H22NO4.ClH/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4;/h5-6,9-12H,7-8H2,1-4H3;1H/q+1;/p-1
• Clé InChI: RLQYRXCUPVKSAW-UHFFFAOYSA-M

Description

Description générale

Palmatineis an isoquinoline alkaloid. Palmatine chloride (PMTCl) is a protoberberine isoquinoline alkaloid with no ketone group and a soluble drug form of palmatine. It has low hygroscopic stability because of chloride ions present in its structure. PMTCl is a natural compound found in the rhizomes of Coptischinensis.

Application

Palmatine chloride has been used to test its effects as an inhibitor of soluble epoxide hydrolase (sEH) in vitro.

Actions biochimiques/physiologiques

Palmatine chloride acts as a microbial collagenase inhibitor and a potential anti-infective agent. It possesses many other pharmacological properties such as antioxidant, anti-inflammatory, anticancer, anti-viral, and neuroprotective.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302
• Conseils de prudence: P264 - P270 - P301 + P312 - P501
• Classification des risques: Acute Tox. 4 Oral
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable