SAB5701923

Anti-Phospho-CDC25A-S76 antibody produced in rabbit

• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: liquid
• Espèces réactives: mouse, rat, human
• Concentration: 1.51 mg/mL
• Technique(s): western blot: 1:500-1:2000
• Numéro d'accès UniProt: P30304
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pSer76)
• Informations sur le gène: human ... CDC25A(993)

Description

Description générale

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

Immunogène

A phospho specific peptide corresponding to residues surrounding S76 of human CDC25A

Forme physique

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable