SAB4700229

Monoclonal Anti-CD79A antibody produced in mouse

clone HM47, purified immunoglobulin, buffered aqueous solution

• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: HM47, monoclonal
• Forme: buffered aqueous solution
• Espèces réactives: pig, human, mouse
• Concentration: 1 mg/mL
• Technique(s): flow cytometry: suitable
• Isotype: IgG1
• Numéro d'accès NCBI: NM_001783.3
• Numéro d'accès UniProt: P11912
• Conditions d'expédition: wet ice
• Température de stockage: 2-8°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... CD79A(973)

Description

Description générale

Cluster of differentiation 79A (CD79A), also known as mb-1 gene, is encoded by the gene mapped to human chromosome 19q13.2-13.3. The encoded protein is characterized with a single extracellular immunoglobulin domain, a transmembrane domain and an intracytoplasmic signaling domain with an immunoreceptor tyrosine-based activation motif (ITAM).

The antibody HM47 interacts with CD79a (Ig alpha), a 40-45 kDa subunit of B cell antigen-specific receptor (BCR) and its early developmental forms.

Immunogène

Synthetic peptide corresponding to amino acids 208-222 of human CD79a

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Actions biochimiques/physiologiques

Cluster of differentiation 79A (CD79A) functions as a highly lineage-specific marker of B lymphoid cells. It also plays a crucial role in the diagnosis of acute leukemia. Mutations in the gene might be a cause of agammaglobulinemia. CD79A acts as an potential biomarker for the detection of B lineage neoplasms.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable