D5038

2′-Deoxyguanosine 5′-triphosphate trisodium salt solution

100 mM (pH 7)

• Synonyme(s) : dGTP-Na₃
• Formule empirique (notation de Hill): C₁₀H₁₃N₅Na₃O₁₃P₃
• Numéro CAS: 93919-41-6
• Poids moléculaire : 573.13
• Numéro CE : 300-026-5
• Numéro MDL: MFCD00080337
• Code UNSPSC : 41106305
• ID de substance PubChem : 24893919
• Nomenclature NACRES : NA.52

Propriétés

• Pureté: ≥99%
• Forme: liquid
• Concentration: 100 mM (pH 7)
• Couleur: colorless
• Activité étrangère: DNase, RNase, none detected
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [Na+].[Na+].[Na+].NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)O3)C(=O)N1
• InChI: 1S/C10H16N5O13P3.3Na/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(26-6)2-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h3-6,16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,17);;;/q;3*+1/p-3/t4-,5+,6+;;;/m0.../s1
• Clé InChI: IWGGLKOTEOCWQP-BIHLCPNHSA-K

Description

Description générale

2′-Deoxyguanosine 5′-triphosphate (dGTP) is made of a guanine nucleobase attached to deoxyribose and a 5′-hydroxyl on the sugar linked to a chain of three phosphate residues. It is used by the cells for the synthesis of DNA with the help of DNA polymerase.

Application

2′-Deoxyguanosine 5′-triphosphate trisodium salt is utilized for methods such as DNA sequencing, PCR and other DNA polymerase based DNA synthesis and repair techniques.

2′-Deoxyguanosine 5′-triphosphate trisodium salt solution has been used:

• in a reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.
• as a component of the PCR mix for in situ reverse transcription-polymerase chain reaction (RT-PCR) amplification of mRNA from prokaryotic and eukaryotic ribosomes
• to study the mutations in the HBB gene via amplification refractory mutation system (ARMS)-PCR

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)