68957
Tris(2-carboxyéthyl)phosphine hydrochloride
BioUltra, suitable for electrophoresis, SDS-PAGE tested
Synonyme(s) :
TCEP
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About This Item
Formule empirique (notation de Hill):
C9H15O6P · HCl
Numéro CAS:
Poids moléculaire :
286.65
Numéro Beilstein :
3724376
Numéro MDL:
Code UNSPSC :
12352128
ID de substance PubChem :
Nomenclature NACRES :
NA.32
Produits recommandés
Gamme de produits
BioUltra
Pureté
97.5-102.5%
Forme
powder
Technique(s)
electrophoresis: suitable
Solubilité
H2O: soluble
Adéquation
SDS-PAGE tested
Chaîne SMILES
Cl[H].OC(=O)CCP(CCC(O)=O)CCC(O)=O
InChI
1S/C9H15O6P.ClH/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15;/h1-6H2,(H,10,11)(H,12,13)(H,14,15);1H
Clé InChI
PBVAJRFEEOIAGW-UHFFFAOYSA-N
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Description générale
Tris(2-carboxyethyl) phosphine hydrochloride (TCEP.HCL ) is a useful reducing agent for Sulphur and nitrogen-containing compounds. TCEP.HCL and the resultant oxide are water-soluble. TCEP.HCL has electron-rich phosphorus and oxygen atoms to combine with various metals, including Rh, Ir, and Pd. It rapidly complexes with Rh and Ir in dioxane at ambient temperature. It reduces disulfide linkages in a range of peptides and proteins in biological disulfide.
Application
TCEP.HCL has been used in various bioconjugation applications, both in vitro and in vivo, to tag proteins and live organisms with great effectiveness under mild physiological circumstances. TCEP.HCL is suitable for varied biological and synthetic applications. At an acidic pH, TCEP.HCL can be used to convert organic disulfides to thiols in water irreversibly.
Water soluble reagent, used for selective reduction of disulfides. More stable than DTT and useful in mass spectrometry applications.
Caractéristiques et avantages
The product has the following benefits:
- TCEP.HCL lowers reactive oxygen species levels.
- It increases glutathione levels and mitochondrial content.
- It has anti-cancer effects.
Remarque sur l'analyse
agarose gel electrophorese corresponds to requirements
Mention d'avertissement
Danger
Mentions de danger
Classification des risques
Eye Dam. 1 - Skin Corr. 1B
Code de la classe de stockage
8A - Combustible corrosive hazardous materials
Classe de danger pour l'eau (WGK)
WGK 1
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