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Key Documents

Y0000017

Propofol for peak identification

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

2,6-Diisopropylphenol, 2,6-Bis(1-methylethyl)phenol, 2,6-Bis(isopropyl)phenol, Propofol

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About This Item

Formule linéaire :
[(CH3)2CH]2C6H3OH
Numéro CAS:
Poids moléculaire :
178.27
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Pression de vapeur

5.6 mmHg ( 100 °C)

Famille d'API

propofol

Fabricant/nom de marque

EDQM

Indice de réfraction

n20/D 1.514 (lit.)

Point d'ébullition

256 °C/764 mmHg (lit.)

Pf

18 °C (lit.)

Densité

0.962 g/mL at 25 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

CC(C)c1cccc(C(C)C)c1O

InChI

1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3

Clé InChI

OLBCVFGFOZPWHH-UHFFFAOYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Propofol for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

235.4 °F - closed cup

Point d'éclair (°C)

113 °C - closed cup


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Lot/Batch Number

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Basic & clinical pharmacology & toxicology, 115(6), 565-570 (2014-06-04)
A variety of techniques have been developed to monitor the depth of anaesthesia. Propofol's pharmacokinetics and response vary greatly, which might be explained by genetic polymorphisms. We investigated the impact of genetic variations on dosage, anaesthetic depth and recovery after
L Muraro et al.
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Canine ovariohysterectomy (OVH) is one of the most commonly performed surgical procedures in companion animal practice. The aim of the study was to determine the frequency and types of complications related to OVH. The clinical records of all street dogs
Eran A Mukamel et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(3), 839-845 (2014-01-17)
Rhythmic oscillations shape cortical dynamics during active behavior, sleep, and general anesthesia. Cross-frequency phase-amplitude coupling is a prominent feature of cortical oscillations, but its role in organizing conscious and unconscious brain states is poorly understood. Using high-density EEG and intracranial
Philippe E Dubois et al.
European journal of anaesthesiology, 31(8), 404-410 (2013-07-26)
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