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T4562

Sigma-Aldrich

Thiamine hydrochloride

meets USP testing specifications

Synonyme(s) :

Aneurine hydrochloride, Vitamin B1 hydrochloride

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About This Item

Formule empirique (notation de Hill):
C12H17ClN4OS · HCl
Numéro CAS:
67-03-8
Poids moléculaire :
337.27
Numéro Beilstein :
3851771
Numéro CE :
200-641-8
Numéro MDL:
MFCD00012780
Code UNSPSC :
12352116
eCl@ss :
34058006
ID de substance PubChem :
24900215
Nomenclature NACRES :
NA.21

Source biologique

synthetic (organic)

Niveau de qualité

200

Agence

USP/NF
meets USP testing specifications

Pureté

98.0-102.0%

Forme

solid

Pf

250 °C (dec.) (lit.)

Application(s)

pharmaceutical (small molecule)

Chaîne SMILES 

CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]

InChI

1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1

Clé InChI

DPJRMOMPQZCRJU-UHFFFAOYSA-M

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Catégories apparentées

Application

Required to support energy metabolism and amino acid synthesis in cultured cells. Present in many classical and serum-free formulations.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H319

Classification des risques

Eye Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
SLCK7986
SLCH7916
SLCF6098
SLBV0751
041M0041V

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Joseph E Kerschner et al.
Archives of otolaryngology--head & neck surgery, 135(1), 33-39 (2009-01-21)
To investigate genetic differences in middle ear mucosa (MEM) with nontypeable Haemophilus influenzae (NTHi) infection. Genetic upregulation and downregulation occurs in MEM during otitis media (OM) pathogenesis. A comprehensive assessment of these genetic differences using the techniques of complementary DNA
Samir Ahmed El-Shazly et al.
International journal of immunopathology and pharmacology, 28(2), 227-239 (2015-03-31)
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia due to abnormalities in either insulin secretion or action. A range of vanadium complexes have been synthesized and demonstrated to be effective in lowering hyperglycemia. Thiamine administration was also
Ashish K Singh et al.
Alcoholism, clinical and experimental research, 38(7), 2127-2137 (2014-06-17)
Chronic ethanol (EtOH) consumption is associated with oxidative tissue damage, decrease in antioxidant enzyme activities, and increase in hepatic and plasma lipids. This study investigates the effect of modified probiotic Escherichia coli Nissle 1917 (EcN) secreting pyrroloquinoline quinone (PQQ) against
Kris Niño G Valdehuesa et al.
Bioprocess and biosystems engineering, 38(9), 1761-1772 (2015-06-07)
Biosynthetic pathways for the production of biofuels often rely on inherent aldehyde reductases (ALRs) of the microbial host. These native ALRs play vital roles in the success of the microbial production of 1,3-propanediol, 1,4-butanediol, and isobutanol. In the present study
Katherine R Heal et al.
Rapid communications in mass spectrometry : RCM, 28(22), 2398-2404 (2014-10-11)
Vitamin B(12) is an essential nutrient for more than half of surveyed marine algae species, but methods for directly measuring this important cofactor in seawater are limited. Current mass spectrometry methods do not quantify all forms of B(12), potentially missing
Afficher tous les articles scientifiques apparentés

Articles

Thiamine in Cell Culture

How thiamine and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of thiamine.

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