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PHR1210

Supelco

Cumene

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

(1-Methylethyl)benzene, 2-Phenylpropane, Isopropylbenzene, NSC 8776

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About This Item

Formule linéaire :
C6H5CH(CH3)2
Numéro CAS:
98-82-8
Poids moléculaire :
120.19
Numéro Beilstein :
1236613
Numéro CE :
202-704-5
Numéro MDL:
MFCD00008881
Code UNSPSC :
41116107
ID de substance PubChem :
329823217
Nomenclature NACRES :
NA.24

Qualité

certified reference material
pharmaceutical secondary standard

Niveau de qualité

300

Agence

traceable to USP 1151709

Densité de vapeur

4.1 (vs air)

Pression de vapeur

8 mmHg ( 20 °C)
9.7 mmHg ( 37.7 °C)

Famille d'API

cumene

CofA (certificat d'analyse)

current certificate can be downloaded

Température d'inflammation spontanée

797 °F

Limite d'explosivité

6.5 %

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Indice de réfraction

n20/D 1.491 (lit.)

Point d'ébullition

152-154 °C (lit.)

Pf

−96 °C (lit.)

Densité

0.864 g/mL at 25 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-30°C

Chaîne SMILES 

CC(C)c1ccccc1

InChI

1S/C9H12/c1-8(2)9-6-4-3-5-7-9/h3-8H,1-2H3

Clé InChI

RWGFKTVRMDUZSP-UHFFFAOYSA-N

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Catégories apparentées

Description générale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Cumene may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAA9023 in the slot below. This is an example certificate only and may not be the lot that you receive.

Mention d'avertissement

Danger

Mentions de danger

H226,H304,H335,H350,H411

Classification des risques

Aquatic Chronic 2 - Asp. Tox. 1 - Carc. 1B - Flam. Liq. 3 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

87.8 °F - closed cup

Point d'éclair (°C)

31.0 °C - closed cup

Choose from one of the most recent versions:

Certificats d'analyse (COA)

Lot/Batch Number
LRAC5121
LRAA9023
P500210

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Determination of Residual Solvents in Bulk Drug and Formulations
Singh P and Sinha M
American Journal of PharmTech Research, 3(4), 289-295 (2006)
A novel peroxy radical based oxidative stressing system for ranking the oxidizability of drug substances
Harmon PA. et al.
Journal of Pharmaceutical Sciences, 95(9), 2014-2028 (2006)
Youji Okada et al.
Organic & biomolecular chemistry, 4(22), 4113-4117 (2007-02-23)
We have undertaken a detailed study of the antioxidant activity of allicin, one of the main thiosulfinates in garlic, in order to obtain quantitative information on it as a chain-breaking antioxidant. The antioxidant actions of allicin against the oxidation of
A Getsoian et al.
International journal of pharmaceutics, 348(1-2), 3-9 (2007-10-20)
To emphasize the fact that solvents can be either critical or immaterial in crystallizing specific polymorphs, a method for obtaining multiple polymorphs of a compound using only one solvent is demonstrated. By varying the crystallization temperature and level of supersaturation
C Holvoet et al.
Die Pharmazie, 62(2), 126-132 (2007-03-08)
Paclitaxel, an antitumoral drug, is poorly soluble in aqueous media. Therefore, in a commercialised formulation (Taxol), paclitaxel (30 mg active compound) is dissolved in polyethoxylated castor oil (Cremophor EL) and ethanol. After dilution of Taxol in aqueous media paclitaxel tends
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