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Key Documents

PHR1229

Supelco

Ethylbenzene

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

Ethylbenzene, NSC 406903, Phenylethane

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About This Item

Formule linéaire :
C6H5C2H5
Numéro CAS:
Poids moléculaire :
106.17
Numéro Beilstein :
1901871
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

certified reference material
pharmaceutical secondary standard

Niveau de qualité

Agence

traceable to USP 1265457

Densité de vapeur

3.7 (vs air)

Pression de vapeur

10 mmHg ( 20 °C)
19 mmHg ( 37.7 °C)

CofA (certificat d'analyse)

current certificate can be downloaded

Température d'inflammation spontanée

810 °F

Limite d'explosivité

6.7 %

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Indice de réfraction

n20/D 1.495 (lit.)

Point d'ébullition

136 °C (lit.)

Pf

−95 °C (lit.)

Densité

0.867 g/mL at 25 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-30°C

Chaîne SMILES 

CCc1ccccc1

InChI

1S/C8H10/c1-2-8-6-4-3-5-7-8/h3-7H,2H2,1H3

Clé InChI

YNQLUTRBYVCPMQ-UHFFFAOYSA-N

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Description générale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards..

Application

Ethylbenzene may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAC3557 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogrammes

FlameExclamation markHealth hazard

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - STOT RE 2

Organes cibles

hearing organs

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

71.6 °F - closed cup

Point d'éclair (°C)

22.0 °C - closed cup


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Certificats d'analyse (COA)

Lot/Batch Number

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Les clients ont également consulté

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A validated GC?MS method for the determination and quantification of residual solvents in counterfeit tablets and capsules.
Deconinck E, et al.
Journal of Pharmaceutical and Biomedical Analysis, 70(1-2), 64-70 (2012)
Static headspace gas chromatographic method for quantitative determination of residual solvents in pharmaceutical drug substances according to European Pharmacopoeia requirements.
Otero R, et al.
Journal of Chromatography A, 1057(1-2), 193-201 (2004)
E Jindrová et al.
Folia microbiologica, 47(2), 83-93 (2002-06-13)
Several aerobic metabolic pathways for the degradation of benzene, toluene, ethylbenzene and xylene (BTEX), which are provided by two enzymic systems (dioxygenases and monooxygenases), have been identified. The monooxygenase attacks methyl or ethyl substituents of the aromatic ring, which are
W Tang et al.
Toxicology, 144(1-3), 39-50 (2000-04-27)
In the present studies, human exposure to styrene and to ethylbenzene (EB) is assessed on the basis of literature data. Total styrene and total EB exposure result from inhalation and from food intake. Styrene and EB inhaled represent the greatest
Leigh Henderson et al.
Mutation research, 635(2-3), 81-89 (2007-05-08)
Ethylbenzene is an important industrial chemical that has recently been classified as a possible human carcinogen (IARC class 2B). It induces tumours in rats and mice, but neither the relevance of these tumours to humans nor their mechanism of induction

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