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Autres documents

C2158000

Cholic acid

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

3α,7α,12α-Trihydroxy-5β-cholanic acid, Cholanic acid

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About This Item

Formule empirique (notation de Hill):
C24H40O5
Numéro CAS:
81-25-4
Poids moléculaire :
408.57
Numéro Beilstein :
2822009
Numéro MDL:
MFCD00003672
Code UNSPSC :
41116107
ID de substance PubChem :
329774969
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Agence

EP Reference Standard

Famille d'API

cholic acid

Fabricant/nom de marque

EDQM

Pf

200-201 °C (lit.)

Application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@]([H])(CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(O)=O

InChI

1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1

Clé InChI

BHQCQFFYRZLCQQ-OELDTZBJSA-N

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Non-denaturing ionic detergent used for extraction of membrane proteins.

Actions biochimiques/physiologiques

Bile Acid

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Nevzat Kazgan et al.
Gastroenterology, 146(4), 1006-1016 (2014-01-07)
Sirtuin 1 (SIRT1), the most conserved mammalian oxidized nicotinamide adenine dinucleotide-dependent protein deacetylase, is an important metabolic sensor in many tissues. However, little is known about its role in the small intestine, which absorbs and senses nutrients. We investigated the
Marcello Sega et al.
The Journal of chemical physics, 138(4), 044110-044110 (2013-02-08)
We present a generalized version of the ITIM algorithm for the identification of interfacial molecules, which is able to treat arbitrarily shaped interfaces. The algorithm exploits the similarities between the concept of probe sphere used in ITIM and the circumsphere
Zheng Pan et al.
Carbohydrate polymers, 94(1), 394-399 (2013-04-03)
Self-assembled amphiphilic N-(2,3-dihydroxypropyl)-chitosan-cholic acid (DHP-CS-CHO) micelle was prepared as a carrier for paclitaxel. DHP-CS-CHO was synthesized by grafted small molecules cholic acid and glycidol onto primary amine group of chitosan, respectively. The DHP-CS-CHO formed uniform micelles (size=212.4±3.1 nm) with a
Bethany P Cummings et al.
Disease models & mechanisms, 6(2), 443-456 (2012-12-25)
Post-operative increases in circulating bile acids have been suggested to contribute to the metabolic benefits of bariatric surgery; however, their mechanistic contributions remain undefined. We have previously reported that ileal interposition (IT) surgery delays the onset of type 2 diabetes
Florence Janvier et al.
Journal of the mechanical behavior of biomedical materials, 18, 100-107 (2012-12-25)
Elevated red blood cell (RBC) aggregation increases low-shear blood viscosity and is closely related to several pathophysiological diseases such as atherosclerosis, thrombosis, diabetes, hypertension, cancer, and hereditary chronic hemolytic conditions. Non-ionic linear polymers such as poly(ethylene glycol) (PEG) and Pluronic
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