92142

Biochanin A

analytical standard

• Synonyme(s) : 4′-Methylgenistein, 5,7-Dihydroxy-4′-methoxyisoflavone, Genistein 4′-methyl ether, Olmelin
• Formule empirique (notation de Hill): C₁₆H₁₂O₅
• Numéro CAS: 491-80-5
• Poids moléculaire : 284.26
• Numéro Beilstein : 278107
• Numéro CE : 207-744-7
• Numéro MDL: MFCD00006839
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 100
• Pureté: ≥95.0% (HPLC)
• Durée de conservation: limited shelf life, expiry date on the label
• Pf: 210-213 °C (lit.)
• Application(s): food and beverages
• Format: neat
• Chaîne SMILES: COc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O
• InChI: 1S/C16H12O5/c1-20-11-4-2-9(3-5-11)12-8-21-14-7-10(17)6-13(18)15(14)16(12)19/h2-8,17-18H,1H3
• Clé InChI: WUADCCWRTIWANL-UHFFFAOYSA-N

Description

Actions biochimiques/physiologiques

Biochanin A is an isoflavone phytoestrogen found in red clover (Trifolium pratense) that is a selective agonist at ER-β estrogen receptors, and may have chemopreventive efficacy against breast cancer. In line with its low activity at ER-α estrogen receptors, it is essentially devoid of uterotrophic activity. Biochanin A is also a ligand for the aryl hydrocarbon receptor (AhR). It reduces arterial resistance and enhances microcirculation perhaps via effects on potassium and/or calcium ion channels. Induction of sulfotransferases for xenobiotic detoxification has been proposed as a mechanism of its cancer preventive effects.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable