MAB3482
Anti-Cystic Fibrosis Transmembrane Conductance Regulator Antibody, clone MM13-4
clone MM13-4, Chemicon®, from mouse
Synonyme(s) :
CFTR
Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
mouse
Niveau de qualité
Forme d'anticorps
purified immunoglobulin
Type de produit anticorps
primary antibodies
Clone
MM13-4, monoclonal
Espèces réactives
human
Ne doit pas réagir avec
mouse, shark
Fabricant/nom de marque
Chemicon®
Technique(s)
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Isotype
IgG1
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... CFTR(1080)
Spécificité
Human cystic fibrosis transmembrane conductance regulator (CFTR). Recognizes an epitope at the N-terminal between residues 24 and 35.
Immunogène
Synthetic peptide (RKGYRQRLELSD) corresponding to residues 25-36 of human cystic fibrosis transmembrane conductance regulator (CFTR).
Application
Detect Cystic Fibrosis Transmembrane Conductance Regulator using this Anti-Cystic Fibrosis Transmembrane Conductance Regulator Antibody, clone MM13-4 validated for use in IC, IP & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Ion Channels & Transporters
Ion Channels & Transporters
Western blot: 10 μg/mL, recognizes CFTR (150-170kDa) and two additional proteins at 52kDa and 38kDa
Immunoprecipitation
Immunofluorescence
Note: Does not work on paraffin embedded tissue.
Optimal working dilutions must be determined by the end user.
Immunoprecipitation
Immunofluorescence
Note: Does not work on paraffin embedded tissue.
Optimal working dilutions must be determined by the end user.
Forme physique
Format: Purified
Purified immunoglobulin. Liquid in 0.02 M Phosphate buffer, 0.25 M NaCl, pH 7.6 with 0.1% sodium azide.
Stockage et stabilité
Maintain at 2-8°C in undiluted aliquots up to 6 months.
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Vous ne trouvez pas le bon produit ?
Essayez notre Outil de sélection de produits.
En option
Réf. du produit
Description
Tarif
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Ion transport mechanisms linked to bicarbonate secretion in the esophageal submucosal glands.
Abdulnour-Nakhoul, S; Nakhoul, HN; Kalliny, MI; Gyftopoulos, A; Rabon, E; Doetjes et al.
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology null
Shipeng Wei et al.
The Journal of biological chemistry, 289(29), 19942-19957 (2014-05-31)
ATP-binding cassette (ABC) transporters are an ancient family of transmembrane proteins that utilize ATPase activity to move substrates across cell membranes. The ABCC subfamily of the ABC transporters includes active drug exporters (the multidrug resistance proteins (MRPs)) and a unique
Nabila Hamdaoui et al.
British journal of pharmacology, 163(4), 876-886 (2011-03-04)
The cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-dependent chloride channel in the plasma membrane of epithelia whose mutation is the cause of the genetic disease cystic fibrosis (CF). The most frequent CFTR mutation is deletion of Phe(508) and
Lianwu Fu et al.
The Biochemical journal, 441(2), 633-643 (2011-10-15)
CFTR (cystic fibrosis transmembrane conductance regulator) is expressed in the apical membrane of epithelial cells. Cell-surface CFTR levels are regulated by endocytosis and recycling. A number of adaptor proteins including AP-2 (μ2 subunit) and Dab2 (Disabled-2) have been proposed to
Jie Ting Zhang et al.
Scientific reports, 7(1), 5233-5233 (2017-07-14)
Cystic fibrosis transmembrane conductance regulator (CFTR), known as a cAMP-activated Cl- channel, is widely expressed at the apical membrane of epithelial cells in a wide variety of tissues. Of note, despite the abundant expression of CFTR in mammalian kidney, the
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
Contacter notre Service technique