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Merck
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Principaux documents

MAB3306

Sigma-Aldrich

Anti-MMP-3 Antibody, cross reacts w/hMMP-10, clone 55-2A4

clone 55-2A4, Chemicon®, from mouse

Synonyme(s) :

Stromelysin-1, Transin, Proteoglycanase

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

55-2A4, monoclonal

Espèces réactives

human, pig, rat, sheep

Ne doit pas réagir avec

bovine, rabbit, mouse

Fabricant/nom de marque

Chemicon®

Technique(s)

ELISA: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

Isotype

IgG1κ

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... MMP3(4314)

Spécificité

The antibody specifically reacts with precursor and active forms of human MMP-3. This is a purified mouse monoclonal antibody to human matrix metalloproteinase 3 (human MMP-3, stromelysin-1) from synovial cells. The antibody cross reacts 34% with human MMP-10.

Immunogène

Epitope: cross reacts w/hMMP-10
Human matrix metalloproteinase 3 (human MMP-3, stromelysin-1) from synovial cells.

Application

Immunoblotting (0.5 μg/mL)

Immunohistochemistry on paraffin-embedded tissues (5-10μg/mL, PLP fixation required, not recommended for traditional formalin fixation. Immunohistochemistry on fresh frozen sections (0.5 μg/mL)

ElA
Research Category
Cell Structure
Research Sub Category
MMPs & TIMPs
This Anti-MMP-3 Antibody, cross reacts w/hMMP-10, clone 55-2A4 is validated for use in ELISA, WB, IH(P) for the detection of MMP-3.

Forme physique

Format: Purified
Liquid in 0.01M Na-Phosphate buffer, pH 7.0, 125 mM NaCl, containing 2% protease free bovine serum albumin.

Stockage et stabilité

Maintain frozen at -20°C in undiluted aliquots for up to 12 months.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Manufactured by Daiichi Fine Chemical Co., Ltd

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

K Obata et al.
Clinica chimica acta; international journal of clinical chemistry, 211(1-2), 59-72 (1992-10-15)
A one-step sandwich enzyme immunoassay (EIA) for matrix metalloproteinase 3 (MMP-3; stromelysin-1) was developed. The assay system used two simultaneous immunoreactions using a solid phase monoclonal antibody and a horseradish peroxidase-labeled monoclonal antibody (Fab'). The sensitivity of the assay system
Christelle Sanchez et al.
Arthritis and rheumatism, 64(4), 1193-1203 (2011-10-29)
Recent data have shown that abnormal subchondral bone remodeling plays an important role in osteoarthritis (OA) onset and progression, and it was suggested that abnormal mechanical pressure applied to the articulation was responsible for these metabolic changes. This study was
Genomic and proteomic profiling of oxidative stress response in human diploid fibroblasts.
Lifang Xie, Ritu Pandey, Beibei Xu, George Tsaprailis, Qin M Chen, Lifang Xie et al.
Biogerontology null
Iraklis Papageorgiou et al.
Nanomaterials (Basel, Switzerland), 4(2), 485-504 (2014-06-16)
Medical interventions for the treatment of spinal disc degeneration include total disc replacement and fusion devices. There are, however, concerns regarding the generation of wear particles by these devices, the majority of which are in the nanometre sized range with
Journal of dental research
Ogbureke, KU; Fisher, LW
Journal of Dental Research null

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