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HCYTAAB-17K

Millipore

MILLIPLEX® Human Cytokine Autoantibody Panel

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About This Item

Nomenclature NACRES :
NA.47

Espèces réactives

human

Fabricant/nom de marque

Milliplex®

Technique(s)

multiplexing: suitable

Méthode de détection

fluorometric (Luminex® xMAP®)

Température de stockage

2-8°C

Description générale

Anti-cytokine antibodies occur frequently and are present in healthy individuals and patients with acquired immunodeficiency and autoimmune diseases. Cytokines offering protection against microbes can be targeted by cytokine autoantibodies, leading to life-threatening infections. Some infections associated with anti-cytokine antibodies include M. tuberculosis, Salmonella, S. aureus. E. coli, Histoplasma, and more. The presence of cytokine autoantibodies in autoimmune disease can influence disease severity and activity. These autoimmune diseases may include systemic lupus erythematosus (SLE), multiple sclerosis (MS), Sjögren′s syndrome, rheumatoid arthritis (RA), and acute respiratory distress syndrome. Measuring cytokine autoantibodies may be useful for disease monitoring and efficacy of treatment.The MILLIPLEX® MAP Human Cytokine Autoantibody Magnetic Bead Panel is a 15-plex kit to be used for the simultaneous detection and profiling of any or all of the following autoantibody analytes in serum and plasma samples: Anti-BAFF, Anti-G-CSF, Anti-IFNβ, Anti-IFNγ, Anti-IL-1α, Anti-IL-6, Anti-IL-8, Anti-IL-10, Anti-IL-12 (p40), Anti-IL-15, Anti-IL-17A, Anti-IL-17F, Anti-IL-18, Anti-IL-22, and Anti-TNFα. For this particular panel, 4 assay control beads are also included as part of the base kit format.

Application

The Human Cytokine Autoantibody panel is a bead-based multiplex assay based on the Luminex® xMAP technology which enables the simultaneous analysis of cytokine autoantibodies in human serum and plasma samples.This is assay yields results in Median Fluorescence Intensity (MFI).Four assay control beads are included in the base kit.This is an overnight or 2 hour incubation assay.This assay requires 25 μL of 1:100 diluted plasma or serum.Analytes available:BAFF/Blys;G-CSF;IFNβ;IFNγ;IL-1α;IL-6;IL-8;IL-10;IL-12 (p40);IL-15;IL-17A;IL-17F;IL-18;IL-22;TNFα

Caractéristiques et avantages

Design your multiplex kit by choosing available analytes within this panel.

Conditionnement

96-well plate

Stockage et stabilité

Recommended storage for kit components is 2 - 8°C.

Informations légales

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictogrammes

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Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Code de la classe de stockage

12 - Non Combustible Liquids

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Contenu apparenté

Multiplex analysis of autoantibodies, such as MILLIPLEX® multiplex assays, helps advance research by detecting multiple autoantibodies like cytokine autoantibodies, autoimmune autoantibodies, and cancer autoantibodies at once to give researchers a full picture of analyte concentrations.

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

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