580217

Taurocholic Acid, Sodium Salt

Detergent useful for the solubilization of lipids and membrane-bound proteins. Aggregation number: 4.

• Synonyme(s) : Taurocholic Acid, Sodium Salt, Sodium Taurocholate
• Formule empirique (notation de Hill): C₂₆H₄₄NO₇S · Na
• Numéro CAS: 145-42-6
• Poids moléculaire : 537.68
• Numéro MDL: MFCD00013050
• Code UNSPSC : 12352106
• Nomenclature NACRES : NA.21

Propriétés

• Niveau de qualité: 100
• Pureté: ≥90% (TLC)
• Forme: solid
• Poids mol.: micellar wt 2100
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; desiccated (hygroscopic)
• Nombre d'agrégation: 4
• Couleur: white
• pKa: 1.9
• CMC: 3 - 11 mM
• Solubilité: water: soluble
• Conditions d'expédition: ambient
• Température de stockage: 2-8°C
• InChI: 1S/C26H45NO7S.Na/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);/q;+1/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;/m1./s1
• Clé InChI: JAJWGJBVLPIOOH-IZYKLYLVSA-M

Description

Description générale

Detergent useful for the solubilization of lipids and membrane–bound proteins. Aggregation number: 4.

Detergent useful for the solubilization of lipids and membrane-bound proteins (aggregation number: 4; CMC: 3-11 mM; micellar weight: 2100; pK_a: 1.9).

Application

• Discovery of Taurocholic Acid Sodium Hydrate as a Novel Repurposing Drug for Intervertebral Disc Degeneration by Targeting MAPK3.: This research highlights the therapeutic potential of taurocholic acid, sodium salt in treating intervertebral disc degeneration. By targeting the MAPK3 pathway, it offers a new approach to managing spinal disorders, reflecting its significance in developing innovative treatments (Li P et al., 2024).


• Effects of extraction methods and particle size distribution on the structural, physicochemical, and functional properties of dietary fiber from deoiled cumin.: This research uses taurocholic acid, sodium salt to investigate the optimization of dietary fiber extraction, contributing to advancements in food chemistry and health-related product development (Ma MM et al., 2016).

Avertissement

Toxicity: Standard Handling (A)

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable