539142

Proteasome Substrate III, Fluorogenic

≥98% (HPLC), amorphous solid, proteasome substrate, Calbiochem^®

• Synonyme(s) : Proteasome Substrate III, Fluorogenic, Suc-LLVY-AMC, Chymotrypsin Substrate III, Fluorogenic
• Formule empirique (notation de Hill): C₄₀H₅₃N₅O₁₀
• Poids moléculaire : 763.88
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• product name: Proteasome Substrate III, Fluorogenic, Proteasome Substrate III, Fluorogenic, is a substrate for proteasome. Also acts as a substrate for calpain, chymotrypsin, and ingensin.
• Niveau de qualité: 100
• Pureté: ≥98% (HPLC)
• Forme: amorphous solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; protect from light
• Couleur: white
• Solubilité: DMSO: 50 mg/mL
• Fluorescence: λ_ex ~380 nm; λ_em ~460 nm
• Conditions d'expédition: ambient
• Température de stockage: −20°C

Description

Description générale

Fluorogenic proteasome substrate. Also acts as a substrate for calpain, chymotrypsin, and ingensin.

Spécificité

Inhibits serine proteases and cysteine proteases.

Actions biochimiques/physiologiques

Cell permeable: no

Primary Target
Proteasome

Product does not compete with ATP.

Reversible: no

Avertissement

Toxicity: Standard Handling (A)

Séquence

Suc-Leu-Leu-Val-Tyr-AMC

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Autres remarques

Anderson, M., et al. 1999. Exp. Eye Res.69, 129.
Rock, K.L., et al. 1994. Cell 78, 761.
Tsubuki, S., et al. 1993. Biochem. Biophys. Res. Commun.196, 1195.
Sasaki, T., et al. 1984. J. Biol. Chem. 259, 12489.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable