407135-M

Caged Ins(1,4,5)P₃, Trisodium Salt

Photolabile derivative of Ins(1,4,5)P₃ that is not biologically active and is not metabolized by endogenous phosphatase.

• Synonyme(s) : Caged Ins(1,4,5)P₃, Trisodium Salt, D- myo-Inositol 1,4,5-Trisphosphate, P ⁴⁽⁵⁾-1-(2-Nitrophenyl)ethyl Ester, 3Na
• Formule empirique (notation de Hill): C₁₄H₁₉NO₁₇P₃ · 3Na
• Poids moléculaire : 635.19
• Code UNSPSC : 12352211

Propriétés

• Niveau de qualité: 100
• Pureté: ≥90% (HPLC)
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; desiccated; protect from light
• Couleur: off-white
• Solubilité: water: 1 mg/mL
• Température de stockage: −20°C

Description

Description générale

Extinction coefficient (265 nm, H₂O): 4240 M^-1cm^-1.

Note: 1 set = 10 x 10 µg.

Photolabile derivative of Ins(1,4,5)P₃ that is not biologically active and is not metabolized by endogenous phosphatase (extinction coefficient: 4240 M^-1cm^-1; 265 nm, H₂O). A mixture of two isomers with a cage on either the 4 or 5 position. Can be selectively released by irradiation with a short pulse of light of about 360 nm to produce a concentration jump of Ins(1,4,5)P₃.

Photolabile derivative of Ins(1,4,5)P₃ that is not biologically active and is not metabolized by endogenous phosphatase. A mixture of two isomers with a cage present on either the 4 or 5 position. Can be selectively released by irradiation with a short pulse of light of about 360 nm to produce a concentration jump of Ins(1,4,5)P₃.

Actions biochimiques/physiologiques

Primary Target
Photolabile derivative of Ins(1,4,5)P3 that is not biologically active

Avertissement

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Autres remarques

Walker, J.W., et al. 1987. Nature327, 249.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable