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137119

SAFC

Phospho-L-Tyrosine Disodium Salt

EMPROVE® EXPERT

Fabrication pharma

Synonyme(s) :

Phospho-L-tyrosine disodium salt, PTyr, Phospho-Tyrosine, Phosphotyrosine

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About This Item

Formule empirique (notation de Hill):
C9H10NNa2O6P
Numéro CAS:
1610350-91-8
Poids moléculaire :
305.13
Code UNSPSC :
12352209

Source biologique

synthetic

Niveau de qualité

500

Gamme de produits

EMPROVE® EXPERT

Forme

powder or crystals

Conditionnement

pkg of 1 kg (in PE drum, 2 inner PE liners 1371191000)
pkg of 10 kg (in PE drum, 2 inner PE liners 1371199010)
pkg of 100 g (in PE tub, inner glas bottle 1371190100)

pH

5.5-9.0 (10 g/L in H2O)

Solubilité

25 g/L
 ≤70 g/L (in complex feed)

Adéquation

suitable for manufacturing use (cell culture)

Température de stockage

2-8°C

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Description générale

Modified amino acids are inhouse manufactured amino acid derivatives with specific properties enabling the intensification of cell culture processes.

Together with the companion product Sulfo-Cysteine sodium salt, the new modified amino acid Phospho-Tyrosine disodium salt can be used as replacement for tyrosine to generate highly concentrated, neutral pH feeds. Both modified amino acids eliminate the need for alkaline feeds, which are normally applied to ensure solubility and stability of the unmodified amino acids tyrosine and cysteine.
Our SAFC® portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.

M-Clarity Program

As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Caractéristiques et avantages

  • Reduced complexity in fed-batch process
  • High concentrations of modified tyrosine in main feeds at neutral pH
  • Enhanced solubility up to 70g/l in complex feed
  • Prevention of caustic shocks in the bioreactor due to high pH feeds
  • More convenient preparation process with less contamination risks
  • Higher feed stability at room temperature

Liaison

Webinar

Title: Simplification of Fed-Batch Processes Using Modified Amino Acids

Informations légales

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

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