1.11714

3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide

for biochemistry

• Synonyme(s) : 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide, Thiazolyl blue, MTT
• Formule empirique (notation de Hill): C₁₈H₁₆BrN₅S
• Numéro CAS: 298-93-1
• Poids moléculaire : 414.32
• Numéro MDL: MFCD00011964
• Code UNSPSC : 12352107
• Numéro de classement CE : 206-069-5

Propriétés

• Niveau de qualité: 100
• Forme: solid
• Pf: 195 °C
• Solubilité: 10 g/L
• Température de stockage: 2-30°C
• InChI: 1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1
• Clé InChI: AZKSAVLVSZKNRD-UHFFFAOYSA-M

Description

Application

<ul>
<li><strong>Anal Biochem, 2017</strong>: Comparison of MTT and Neutral Red assays to assess cell viability in the presence of copper compounds, highlighting the versatility and sensitivity of the MTT assay in cytotoxicity testing (Gomez Perez et al., 2017).</li>
<li><strong>Indian J Pharmacol, 2016</strong>: Evaluation of the cytotoxic potential of various Indian fruit peels on liver cancer cells (HepG2) using MTT assay, providing insights into natural product research and potential anticancer properties (Garg et al., 2016).</li>
<li><strong>ACS Appl Mater Interfaces, 2015</strong>: Application in the real-time evaluation of live cancer cells, combining surface plasmon resonance and electrochemical methodologies with MTT assays for enhanced accuracy in viability testing (Wu et al., 2015).</li>
</ul>

Remarque sur l'analyse

Assay (argentometric): ≥ 98
Identity (IR-spectrum): passes test
Spec. Absorptivity A 1%/1cm (242 nm; 0.001 %; 1 cm; methanol): 480 - 530
Heavy metals (as Pb): ≤ 0.001 %
Sulfated ash: ≤ 0.5 %

Informations sur la sécurité

• Pictogrammes: GHS07,GHS08
• Mention d'avertissement: Warning
• Mentions de danger: H315 - H319 - H335 - H341
• Conseils de prudence: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Classification des risques: Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable