TP53
tumor protein p53
Synonymes:
BCC7, LFS1, P53, TRP53
Espèce(s):
Human TP53 (7157), Rat Tp53 (24842), Zebrafish tp53 (30590), Horse TP53 (100062044), domestic cat TP53 (493847), dog TP53 (403869), chicken TP53 (396200), cow TP53 (281542), sheep TP53 (443421), domestic guinea pig Tp53 (100379269) ...Plus
ID UniProtKB:
ID du gène:
- Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
- Rat(24842) tumor protein p53
- Zebrafish(30590) tumor protein p53
- Horse(100062044) tumor protein p53
- domestic cat(493847) tumor protein p53
- dog(403869) tumor protein p53
- chicken(396200) tumor protein p53
- cow(281542) tumor protein p53
- sheep(443421) tumor protein p53
- domestic guinea pig(100379269) tumor protein p53
- Domestic Rabbit(100009292) tumor protein p53
- naked mole-rat(101701769) tumor protein p53
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ELISA
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anticorps anti-p53 (de type sauvage), clone PAb1620, clone Pab1620, from mouse,
Espèces réactives
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-p53 Antibody, aa 211-220, clone240, clone PAb240, Chemicon®, from mouse,
Espèces réactives
bovine, chicken, hamster, human, monkey, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1), liquid, clone DO-1, Calbiochem®,
Espèces réactives
feline, human
Application
Anti-Acetyl-p53-K382 Antibody, clone 0, Rabbit Monoclonal, ,
Espèces réactives
mouse
Application
Cell Lines
Small Molecule - Inhibitor
Référence du produit
Description
Espèce(s)
Proteins
Référence du produit
Description
Espèce(s)
p53 Protein, 10 µg, Full length, recombinant human p53. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.,
Espèce(s)
p53 human, recombinant, expressed in E. coli, buffered aqueous glycerol solution,
Espèce(s)
human
p53 (1-81), mutant, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Espèce(s)
human
esiRNA
Référence du produit
Description
Espèce(s)