SAB5702066

Anti-Acetyl-p53-K382 Antibody, clone 0, Rabbit Monoclonal

• Synonyme(s) : BCC7,LFS1,P53,TRP53,p53,TP53,BMFS5
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.46

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Matériaux: colorless
• Clone: 7Z8X9, monoclonal
• Forme: liquid
• Poids mol.: 53 kDa
• Espèces réactives: mouse, mouse
• Concentration: 0.90 mg/mL
• Couleur: colorless
• Isotype: IgG
• Séquence immunogène: HKKLM
• Numéro d'accès UniProt: P04637
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... TP53(7157)

Description

Description générale

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).

Immunogène

A synthetic acetylated peptide around K382 of human p53 (NP_000537.3).

PBS with 0.05% proclin300,50% glycerol,pH7.3.

Application

DB, WB

Informations sur la sécurité

• Pictogrammes: GHS07,GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H317,H411
• Conseils de prudence: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Classification des risques: Aquatic Chronic 2 - Skin Sens. 1
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3