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Key Documents

SAB4300167

Sigma-Aldrich

Anti-phospho-CDKN1B (pThr187) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-CDKN4 antibody produced in rabbit, Anti-KIP1 antibody produced in rabbit, Anti-MEN1B antibody produced in rabbit, Anti-MEN4 antibody produced in rabbit, Anti-cyclin-dependent kinase inhibitor 1B (p27, Kip1) antibody produced in rabbit

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About This Item

MDL number:
MFCD00284080
UNSPSC Code:
12352203
NACRES:
NA.43

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~27 kDa

species reactivity

human

concentration

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(E-Q-TP-P-K)

NCBI accession no.

NP_004055.1

UniProt accession no.

P46527

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pThr187)

Gene Information

human ... CDKN1B(1027)

Immunogen

Peptide sequence around phosphorylation site of threonine 187 (E-Q-T(p)-P-K), according to the protein CDKN1B.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Target description

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Naomi Oi et al.
Carcinogenesis, 38(7), 728-737 (2017-06-03)
Leukotriene A4 hydrolase (LTA4H), a bifunctional zinc metallo-enzyme, is reportedly overexpressed in several human cancers. Our group has focused on LTA4H as a potential target for cancer prevention and/or therapy. In the present study, we report that LTA4H is a

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