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C1013

Sigma-Aldrich

Carrageenan

suitable for gel preparation

Synonym(s):

Vegetable gelatin

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

algae (red)

description

Predominantly κ and lesser amounts of λ carrageenan

form

powder

color

white to light brown

useful pH range

7.5-10.5 (1.5% in water)

cation traces

Ca: <3.5%
K: <11%
Na: <2.0%

suitability

suitable for gel preparation

storage temp.

room temp

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General description

Carrageenans are mucopolysaccharides from the cell walls of the red algae. They are anionic linear polymers composed of 1,3α-1,4β-galactans having one (κ-), two (ι-) or three (λ-) sulfates per disaccharide unit. In ionic solutions, κ- and ι-carrageenans self-associate into helical structures that form rigid or flexible gels, respectively. λ-carrageenans do not form helices and are non-gelling. Carrageenans are used commercially as thickeners and stabilizing agents.

Application

Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. As ι-, κ-, and λ-carrageenans have varying degress of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities.
Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. As ι-, κ-, and λ- carrageenans have varying degrees of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities. Carrageenan may be used in the development of biomaterials such as bone graft substitutes; entrapping vessels such as biobeads and encapsulation vehicles for drug delivery. Carrageenan be used to develop hydrogels.

Preparation Note

Blended from various seaweeds to produce rigid gels.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Ahu Uraz et al.
Journal of clinical and experimental dentistry, 5(1), e23-e29 (2014-01-24)
The objective of this study was to histologically and histomorphometrically evaluate the efficacy of the new formulations of eggshell-derived calcium carbonate in rats. The study was conducted on 30 adult male rats. Four standardized and circular intrabony defects were created
José A Fernández-Romero et al.
Antimicrobial agents and chemotherapy, 56(1), 358-368 (2011-11-09)
Topical microbicides that block the sexual transmission of HIV and herpes simplex virus 2 (HSV-2) are desperately needed to reduce the incidence of HIV infections worldwide. Previously we completed phase 3 testing of the carrageenan-based gel Carraguard. Although the trial
S Nicklin et al.
Food additives and contaminants, 6(4), 425-436 (1989-10-01)
Carrageenans are a group of high molecular weight sulphated polygalactans which find extensive use in the food industry as thickening, gelling and protein-suspending agents. Although there is no evidence to suggest that the persorption of small amounts of carrageenans across
Bangde Li et al.
PloS one, 8(1), e54975-e54975 (2013-01-30)
Topical microbicides are a promising solution to address the global threat of HIV and other sexually transmitted infections. To be successful, a microbicide not only needs to be biologically functional but also highly acceptable to users. User acceptability of microbicides
Reuben H Fan et al.
NMR in biomedicine, 21(6), 566-573 (2007-11-29)
Integrated diffusion tensor T(2) measurements were made on normal and edematous rat muscle, and the data were fitted with one- and two-compartment models, respectively. Edematous muscle exhibited a short-lived component (T(2) = 28 +/- 6 ms), with diffusion characteristics similar

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