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921815

Sigma-Aldrich

Pearl-chain mixer

Fluidic 658, PC

Synonym(s):

Microfluidic chip

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Microfludic chip x1

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Application

Microfluidic generation of droplets can produce highly monodispersed droplets with high frequency (up to hundreds of kHz). Interest in droplet-based microfluidic systems has grown substantially, because microfluidics offers the ability to handle very small volumes (μl to fl) of fluids, provides better mixing, encapsulation, sorting, and sensing. Microfluidics can be used for high throughput experimentation. Microfluidic-based droplets have many applications, including micro and nanoparticle synthesis and chemical analysis. Highly controlled droplet production also makes single cell analysis, or drug testing possible.

Pearl-chain mixer, Fluidic 658, PC is made of PC (polycarbonate). The Pearl-Chain Mixer Fl. 658 enables mixing of two liquids which is facilitated by an elongated pearl-chain unit. As flows in microchannels are normally laminar, the task of these mixers lies in the improvement of the diffusion condition, e.g. by allowing a long co-flow of the liquids and by adding structures to increase lateral velocity.

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Recent advances of controlled drug delivery using microfluidic platforms.
Li X, et al.
Advanced Drug Delivery Reviews, 128, 3-28 (2018)
Microfluidic-assisted fabrication of carriers for controlled drug delivery.
Santos H A, et al.
Lab on a chip, 17, 1856-1883 (2017)
Sharma T Sanjay et al.
Advanced drug delivery reviews, 128, 3-28 (2017-09-19)
Conventional systematically-administered drugs distribute evenly throughout the body, get degraded and excreted rapidly while crossing many biological barriers, leaving minimum amounts of the drugs at pathological sites. Controlled drug delivery aims to deliver drugs to the target sites at desired
Dongfei Liu et al.
Lab on a chip, 17(11), 1856-1883 (2017-05-10)
The microfluidic technique has brought unique opportunities toward the full control over the production processes for drug delivery carriers, owing to the miniaturisation of the fluidic environment. In comparison to the conventional batch methods, the microfluidic setup provides a range

Articles

Microfluidics for Nanoencapsulation of Nucleic Acids Using Polymeric Carriers

Microfluidic assembly can efficiently overcome the general disadvantages of polyamine nanoencapsulation of nucleic acids, such as a less defined morphology and composition, polydispersity, and poor reproducibility.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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