U211030

DMT-2′O-TBDMS-rU-phosphoramidit

configured for ABI

• Synonym(e): 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-uridin, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit], DMT-2′-O-TBDMS-rU-amidit
• Empirische Formel (Hill-System): C₄₅H₆₁N₄O₉PSi
• CAS-Nummer: 118362-03-1
• Molekulargewicht: 861.05
• MDL-Nummer: MFCD00080343
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329827597
• NACRES: NA.51

Eigenschaften

• Biologische Quelle: non-animal source (no BSE/TSE risk)
• Qualitätsniveau: 300
• Produktlinie: Proligo Reagents
• Assay: ≥99% (³¹P-NMR); ≥99.0% (reversed phase HPLC)
• Form: powder
• Methode(n): oligo synthesis: suitable
• Verunreinigungen: ≤0.3% water content (Karl Fischer); ≤0.5% P(III) Impurities 100-169ppm (³¹P-NMR); ≤0.5% single Impurity (reversed phase HPLC); ≤3% residual Solvent content
• Farbe: white to off-white
• λ: conforms (UV/VIS Identity)
• Eignung: conforms to structure for H-NMR; conforms to structure for LC-MS
• Kompatibilität: configured for ABI
• Nukleosidprofil: base: uridine; base protecting group: none; 2' protecting group: TBDMS; 5' protecting group: DMT; deprotection: fast/standard
• Lagertemp.: −20°C
• SMILES String: COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=CC(=O)NC3=O)(c4ccccc4)c5ccc(OC)cc5
• InChI: 1S/C45H61N4O9PSi/c1-31(2)49(32(3)4)59(55-29-15-27-46)57-40-38(56-42(48-28-26-39(50)47-43(48)51)41(40)58-60(10,11)44(5,6)7)30-54-45(33-16-13-12-14-17-33,34-18-22-36(52-8)23-19-34)35-20-24-37(53-9)25-21-35/h12-14,16-26,28,31-32,38,40-42H,15,29-30H2,1-11H3,(H,47,50,51)/t38-,40-,41-,42-,59?/m1/s1
• InChIKey: SKNLXHRBXYGJOC-ZMHKPELYSA-N

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable