T4580

Tiludronate disodium salt hydrate

≥98% (HPLC)

• Synonym(e): Skelid, Tiludronic acid disodium, [[(4-Chlorophenyl)thio]methylene]bisphosphonic acid disodium salt hydrate
• Empirische Formel (Hill-System): C₇H₇ClNa₂O₆P₂S · xH₂O
• CAS-Nummer: 89987-06-4
• Molekulargewicht: 362.57 (anhydrous basis)
• MDL-Nummer: MFCD16872037
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329826798
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to off-white
• Löslichkeit: H₂O: >10 mg/mL, clear
• Ersteller: Sanofi Aventis
• SMILES String: O.[Na+].[Na+].OP([O-])(=O)C(Sc1ccc(Cl)cc1)P(O)([O-])=O
• InChI: 1S/C7H9ClO6P2S.2Na.H2O/c8-5-1-3-6(4-2-5)17-7(15(9,10)11)16(12,13)14;;;/h1-4,7H,(H2,9,10,11)(H2,12,13,14);;;1H2/q;2*+1;/p-2
• InChIKey: SZVJRJRMQCKFON-UHFFFAOYSA-L

Beschreibung

Biochem./physiol. Wirkung

Tiludronate is a bisphosphonate bone resorption inhibitor. Tiludronate inhibits protein-tyrosine-phosphatase, leading to detachment of osteoclasts from the bone surface. It also inhibits the osteoclastic proton pump and is used to treat Paget′s disease.

Leistungsmerkmale und Vorteile

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Angaben zur Herstellung

Tiludronate disodium salt hydrate is soluble in DMSO at a concentration that is greater than or equal to 10 mg/ml.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable