SRP8044

CD40L, Soluble human

recombinant, expressed in CHO cells, FLAG^® tagged, >95% (SDS-PAGE)

• Synonym(e): ACRP30headless:CD154, ACRP30headless:CD40L, ACRP30headless:TNFSF5, ADIPOQ-CD40L
• UNSPSC-Code: 12352200

Eigenschaften

• Biologische Quelle: human
• Rekombinant: expressed in CHO cells
• Markierung: FLAG^® tagged
• Assay: >95% (SDS-PAGE)
• Form: lyophilized
• Mol-Gew.: 35-40 kDa by SDS-PAGE
• Verpackung: pkg of 10 μg
• Lagerbedingungen: avoid repeated freeze/thaw cycles
• Verunreinigungen: <0.01 EU/μg endotoxin, tested
• UniProt-Hinterlegungsnummer: P29965
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... CD40LG(959)

Beschreibung

Allgemeine Beschreibung

CD40L (cluster of differentiation 40 ligand) belongs to the tumor necrosis factor (TNF) family, and is expressed by basophils, B cells, monocytic cells, natural killer cells, platelets, mast cells and T cells. It is predominantly expressed on pro-inflammatory T cells. It also exists in a soluble form.

Biochem./physiol. Wirkung

CD40L (cluster of differentiation 40 ligand) is active in its membrane-bound form. It interacts with CD40 and functions as a proinflammatory and procoagulant agent. The serum levels of soluble CD40L is elevated in malignant middle cerebral artery infarction (MMCAI) patients, especially in non-surviving patients.

Physikalische Form

Lyophilized from PBS

Rekonstituierung

Reconstitute with 100 μL deionized water.

Sonstige Hinweise

Human CD40L (aa 116-261) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG^®-tag.

Rechtliche Hinweise

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable