SRP6340

IL18BP human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• Synonym(e): IL18BPa, Interleukin-18-binding protein
• UNSPSC-Code: 12352200
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: human
• Rekombinant: expressed in E. coli
• Assay: ≥90% (SDS-PAGE)
• Form: liquid
• Mol-Gew.: 20 kDa (187 aa, 31-194 aa + His Tag)
• Verpackung: pkg of 100 μg
• Konzentration: 1 mg/mL
• UniProt-Hinterlegungsnummer: O95998
• Versandbedingung: dry ice
• Lagertemp.: −70°C
• Angaben zum Gen: human ... IL18BP(10068)

Beschreibung

Allgemeine Beschreibung

IL18BP functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn′s disease. Recombinant human IL18BP protein, fused to His-tag at N-terminus, was expressed in E.coli.

Physikalische Form

1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable