SRP6161

FGF-7 human

recombinant, expressed in human cells, ≥95% (SDS-PAGE)

• Synonym(e): Fibroblast growth factor 7, HBGF-7, Heparin-binding growth factor 7, KGF, Keratinocyte growth factor
• UNSPSC-Code: 12352202
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: human
• Rekombinant: expressed in human cells
• Assay: ≥95% (SDS-PAGE)
• Form: lyophilized
• Mol-Gew.: (17 and 30 kDa, monomer, glycosylated)
• Verpackung: pkg of 10 μg
• Methode(n): cell culture | mammalian: suitable
• NCBI-Hinterlegungsnummer: P21781
• UniProt-Hinterlegungsnummer: P21781
• Versandbedingung: dry ice
• Lagertemp.: −70°C
• Angaben zum Gen: human ... FGF7(2252)

Beschreibung

Allgemeine Beschreibung

Fibroblast growth factor-7 (FGF-7) is a member of the fibroblast growth factor family. FGF family members possess broad mitogenic and cell survival activities. The gene encoding this protein is localized on human chromosome 15q21.1.

Biochem./physiol. Wirkung

Fibroblast growth factor (FGF) family members are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. This protein associates with and activates fibroblast growth factor receptors (FGFRs). Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, re-epithelialization of wounds, hair development and early lung organogenesis.

Physikalische Form

Lyophilized from a PBS solution.

Angaben zur Herstellung

Centrifuge the vial prior to opening.

Rekonstituierung

Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable