SRP6092

FKBP1B human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• Synonym(e): FKBP12.6, FKBP1L, OTK4, PKBP1IL, Peptidyl prolyl cis-trans isomerase FKBP1B
• UNSPSC-Code: 12352204
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: human
• Rekombinant: expressed in E. coli
• Assay: ≥90% (SDS-PAGE)
• Form: liquid
• Mol-Gew.: 14.2 kDa
• Verpackung: pkg of 100 μg
• NCBI-Hinterlegungsnummer: P68106
• UniProt-Hinterlegungsnummer: P68106
• Versandbedingung: dry ice
• Lagertemp.: −70°C
• Angaben zum Gen: human ... FKBP1B(2281)

Beschreibung

Allgemeine Beschreibung

Peptidyl-prolyl cis-trans isomerase FKBP1B (FKBP1B) belongs to the immunophilin protein family which has a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP1B is a cis-trans prolyl isomerase which binds the immunosuppressants FK506 (tacrolimus) and rapamycin (sirolimus). FKBP1B is extremely similar to the FK506-binding protein 1A. The physiological role of FKBP1B is thought to be in excitation-contraction coupling in cardiac muscle.

Physikalische Form

0.25 mg/mL solution in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT and 20% glycerol.

Angaben zur Herstellung

Centrifuge the vial prior to opening.

Sonstige Hinweise

MGSSHHHHHH SSGLVPRGSH RSMGVEIETI SPGDGRTFPK KGQTCVVHYT GMLQNGKKFD SSRDRNKPFK FRIGKQEVIK GFEEGAAQMS LGQRAKLTCT PDVAYGATGH PGVIPPNATL IFDVELLNLE

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H318
• P-Sätze: P280 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Dam. 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable