SML3381

10-Hydroxy-trans-2-decenoic acid

≥98% (HPLC)

• Synonym(e): (E)-10-Hydroxy-2-decenoic acid, 10-HAD, NSC 87516, Royal jelly acid, Trans-10-hydroxy-2-decenoic acid
• Empirische Formel (Hill-System): C₁₀H₁₈O₃
• CAS-Nummer: 14113-05-4
• Molekulargewicht: 186.25
• MDL-Nummer: MFCD00204506
• UNSPSC-Code: 12352106

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: −20°C
• SMILES String: OCCCCCCC\C=C\C(=O)O
• InChI: 1S/C10H18O3/c11-9-7-5-3-1-2-4-6-8-10(12)13/h6,8,11H,1-5,7,9H2,(H,12,13)/b8-6+
• InChIKey: QHBZHVUGQROELI-SOFGYWHQSA-N

Beschreibung

Biochem./physiol. Wirkung

10-Hydroxy-2-decenoic acid is an orally available royal jelly component that potently inhibits osteoclastogenesis. It binds to free fatty acid receptor 4 (FFAR4) on osteoclasts which inhibits RANKL (receptor activator of nuclear factor-κB (NF-κB) ligand), thereby attenuating the induction of nuclear factor of activated T cells (NFAT) c1. 10-Hydroxy-2-decenoic acid inhibits bone resorption in ovariectomized mice.

Royal jelly component that potently inhibits osteoclastogenesis

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable