SML2841

Tarenflurbil

≥98% (HPLC)

• Synonym(e): (R)-(−)-2-Fluor-α-methyl-4-biphenyl-essigsäure, (R)-2-Flurbiprofen, Tarenflurbil
• Lineare Formel: C₆H₅C₆H₃(F)CH(CH₃)CO₂H
• CAS-Nummer: 51543-40-9
• Molekulargewicht: 244.26
• MDL-Nummer: MFCD00869714
• UNSPSC-Code: 12352200

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: C[C@@H](C(O)=O)c1ccc(c(F)c1)-c2ccccc2
• InChI: 1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m1/s1
• InChIKey: SYTBZMRGLBWNTM-SNVBAGLBSA-N

Beschreibung

Biochem./physiol. Wirkung

Tarenflurbil (or R-flurbiprofen) is an R enantiomer of racemic NSAID flurbiprofen that does not inhibit either cyclooxygenase 1 (COX-1) or cyclooxygenase 2 (COX-2). Tarenflurbil potently reduces levels of beta amyloid in human cells through direct inhibition of γ-secretase.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H301 + H311 - H317 - H361d
• P-Sätze: P202 - P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Repr. 2 - Skin Sens. 1B
• Lagerklassenschlüssel: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable