SML2438

Magnolin

≥95% (HPLC)

• Synonym(e): Magnolin, (1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)-tetrahydro-4-(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan, Medioresinoldimethylether
• Empirische Formel (Hill-System): C₂₃H₂₈O₇
• CAS-Nummer: 31008-18-1
• Molekulargewicht: 416.46
• MDL-Nummer: MFCD07783722
• UNSPSC-Code: 12352200

Eigenschaften

• Assay: ≥95% (HPLC)
• Form: powder
• Optische Aktivität: [α]/D +46 to +56°, c = 0.5 in chloroform-d
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: −20°C
• SMILES String: [H][C@]12[C@]([C@@H](C3=CC(OC)=C(OC)C(OC)=C3)OC2)([H])CO[C@@H]1C4=CC=C(OC)C(OC)=C4
• InChI: 1S/C23H28O7/c1-24-17-7-6-13(8-18(17)25-2)21-15-11-30-22(16(15)12-29-21)14-9-19(26-3)23(28-5)20(10-14)27-4/h6-10,15-16,21-22H,11-12H2,1-5H3/t15-,16-,21+,22+/m0/s1
• InChIKey: MFIHSKBTNZNJIK-RZTYQLBFSA-N

Beschreibung

Biochem./physiol. Wirkung

Magnolin is a main component of Magnolia flos the exhibits anti-inflammatory, antioxidative, and vasodilatory activities. Magnolin inhibits cell migration and invasion by targeting the ERKs/RSK2 signaling. Also magnolin protects against renal tubular necrosis, apoptosis, and the deterioration of renal function in contrast-induced nephropathy (CIN) in rats.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable