SML1874

DM-NOFD

≥98% (HPLC)

• Synonym(e): Dimethyl N-oxalyl-D-phenylalanine, N-(2-Methoxy-2-oxoacetyl)-D-phenylalanine methyl ester, N-Oxalyl-D-phenylalanine dimethyl ester
• Empirische Formel (Hill-System): C₁₃H₁₅NO₅
• CAS-Nummer: 865488-53-5
• Molekulargewicht: 265.26
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: oil
• Farbe: , colorless to dark yellow
• Lagertemp.: 2-8°C
• SMILES String: O=C(C(N[C@H](CC1=CC=CC=C1)C(OC)=O)=O)OC

Beschreibung

Allgemeine Beschreibung

Dimethyl N-oxalyl-D-phenylalanine (DM-NOFD) is a small FIH (factor-inhibiting) inhibitor molecule.

Biochem./physiol. Wirkung

DM-NOFD is a cell penetrant, prodrug of NOFD a potent and selective inhibitor of an asparaginyl hydroxylase FIH (factor-inhibiting HIF). DM-NOFD efficiently reduces HIF1a CAD (C-terminal activating domain) hydroxylation in MCF-7 cells.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable