SML1809

PPTN trifluoroacetate salt

≥98% (HPLC)

• Synonym(e): 4-[4-(4-Piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxylic acid trifluoroacetate salt
• Empirische Formel (Hill-System): C₂₉H₂₄F₃NO₂ · C₂HF₃O₂
• CAS-Nummer: 1160271-30-6
• Molekulargewicht: 589.52
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 10 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: OC(C1=CC2=CC(C3=CC=C(C(F)(F)F)C=C3)=CC=C2C(C4=CC=C(C5CCNCC5)C=C4)=C1)=O.FC(F)(C(O)=O)F

Beschreibung

Biochem./physiol. Wirkung

PPTN is a very potent (IC₅₀ = 1 nM) P2Y14 receptor antagonist that does not interact with any other P2Y receptor at concentrations up to 10 μM. PPTN blocks UDP-glucose inhibition of forskolin-induced cAMP accumulation, and neutrophil chemotaxis towards UDP-glucose gradients with nM potency.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable