SML0916

CaCCinh-A01

≥98% (HPLC)

• Synonym(e): 6-(1,1-Dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid
• Empirische Formel (Hill-System): C₁₈H₂₁NO₄S
• CAS-Nummer: 407587-33-1
• Molekulargewicht: 347.43
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 20 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: [s]1c2c(c(c1NC(=O)c3[o]ccc3)C(=O)O)CCC(C2)C(C)(C)C
• InChI: 1S/C18H21NO4S/c1-18(2,3)10-6-7-11-13(9-10)24-16(14(11)17(21)22)19-15(20)12-5-4-8-23-12/h4-5,8,10H,6-7,9H2,1-3H3,(H,19,20)(H,21,22)
• InChIKey: ACLUEOBQFRYTQS-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

CaCCinh-A01 is a TMEM16A (transmembrane member 16A) inhibitor. It also blocks anoctamin-1 (ANO1) and decreases cell viability and represses cell migration.

CaCCinh-A01 is a potent calcium-activated chloride channel (CaCC) inhibitor that fully inhibits CaCC current in human bronchial and intestinal cells. CaCCinh-A01 does not inhibit CFTR.

CaCCinh-A01 is a potent calcium-activated chloride channel (CaCC) inhibitor.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable