SML0739

TAPI-1 acetate salt

≥97% (HPLC)

• Synonym(e): N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-L-Alaninamide acetate salt
• Empirische Formel (Hill-System): C₂₆H₃₇N₅O₅ · xC₂H₄O₂
• CAS-Nummer: 163847-77-6
• Molekulargewicht: 499.60 (free base basis)
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥97% (HPLC)
• Form: powder
• Farbe: white to beige
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• InChI: 1S/C26H37N5O5/c1-16(2)12-21(15-23(32)31-36)25(34)30-22(26(35)29-17(3)24(33)28-11-10-27)14-18-8-9-19-6-4-5-7-20(19)13-18/h4-9,13,16-17,21-22,36H,10-12,14-15,27H2,1-3H3,(H,28,33)(H,29,35)(H,30,34)(H,31,32)/t17-,21+,22-/m0/s1
• InChIKey: AWNBSWDIOCXWJW-WTOYTKOKSA-N

Beschreibung

Anwendung

TAPI-1 acetate salt has been used as a tumor necrosis factor(TNF)-α convertase/ADAM17/α-secretase (TACE) inhibitor.

Biochem./physiol. Wirkung

TAPI-1 is a potent inhibitor of matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase).

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301
• P-Sätze: P264 - P270 - P301 + P310 - P405 - P501
• Gefahreneinstufungen: Acute Tox. 3 Oral
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable