SML0234

Mitiglinide calcium

≥98% (HPLC)

• Synonym(e): (aS,3aR,7aS)-Octahydro-g-oxo-a-(phenylmethyl)-2H-isoindole-2-butanoic acid calcium salt, KAD 1229, Mitiglinide hemicalcium salt, S 21403, [2(S)-cis]-Octahydro-g-oxo-a-(phenylmethyl)-2H-isoindole-2-butanoic acid calclium salt
• Empirische Formel (Hill-System): C₁₉H₂₄NO₃·0.5Ca
• CAS-Nummer: 145525-41-3
• Molekulargewicht: 334.44
• MDL-Nummer: MFCD09955408
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825247
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Optische Aktivität: [α]/D +5 to +9° (c=1, MeOH)
• Lagerbedingungen: desiccated
• Farbe: white to beige
• Löslichkeit: DMSO: ≥10 mg/mL at warmed to 60 °C
• Lagertemp.: room temp
• SMILES String: O=C(C[C@H](Cc1ccccc1)C(=O)O[Ca]OC(=O)[C@H](CC(=O)N2C[C@H]3CCCC[C@H]3C2)Cc4ccccc4)N5C[C@H]6CCCC[C@H]6C5
• InChI: 1S/2C19H25NO3.Ca/c2*21-18(20-12-15-8-4-5-9-16(15)13-20)11-17(19(22)23)10-14-6-2-1-3-7-14;/h2*1-3,6-7,15-17H,4-5,8-13H2,(H,22,23);/q;;+2/p-2/t2*15-,16+,17-;/m00./s1
• InChIKey: PMRVFZXOCRHXFE-FMEJWYFOSA-L

Beschreibung

Biochem./physiol. Wirkung

Mitiglinide is a drug for the treatment of type 2 diabetes. It is a highly selective KATP channel antagonist Mitiglinide is a hypoglycemic agent that closes adenosine triphosphate (ATP)–sensitive potassium channels (KATP channel s) in the pancreatic β-islet cells.

Leistungsmerkmale und Vorteile

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable