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Merck

SAB4700666

Sigma-Aldrich

Monoclonal Anti-Cytokeratin (Pan-reactive) antibody produced in mouse

clone C-11, purified immunoglobulin, buffered aqueous solution

Synonym(e):

Mouse Anti-Cytokeratin, Pan-reactive Cytokeratin Detection

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

C-11, monoclonal

Form

buffered aqueous solution

Speziesreaktivität

mammals

Konzentration

1 mg/mL

Methode(n)

flow cytometry: suitable

Isotyp

IgG1

Versandbedingung

wet ice

Lagertemp.

2-8°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... KRT1(3848)

Allgemeine Beschreibung

Cytokeratins also known as keratins are filament-forming proteins of epithelial cells. In humans, there are 54 cytokeratins. These proteins are divided in to two sub-categories such as acidic type I keratins and basic-to-neutral type II keratins.
The antibody C-11 reacts with Cytokeratin peptides 4, 5, 6, 8, 10, 13, 18. Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.

Immunogen

Keratin-enriched preparation from human epidermoid carcinoma cell line A431

Anwendung

Monoclonal Anti-Cytokeratin (Pan-reactive) antibody produced in mouse has been used in immunocytochemistry.
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 0.5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Biochem./physiol. Wirkung

Cytokeratins play an essential role in normal tissue structure and function. It also facilitates the maintenance of cell mechanical integrity.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Cytokeratin expression, fibrillar organization, and subtle function in liver cells
Marceau N and Loranger A
Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire, 73, 619-625 (1995)
Evaluation of a simple method for storage of blood samples that enables isolation of circulating tumor cells 96 h after sample collection
Apostolou P
Journal of biological research (Thessalonike?, Greece) (2017)
New consensus nomenclature for mammalian keratins
Schweizer J
The Journal of Cell Biology, 174, 169-174 (2006)
Panagiotis Apostolou et al.
Journal of biological research (Thessalonike, Greece), 24, 11-11 (2017-10-05)
Minimizing the effects of transportation on the properties of biological material is a major challenge for the scientific community. The viability of cells is important in cases where their study is urgent for evaluation of treatment response or for the
Martine Broekema et al.
Kidney international, 68(6), 2572-2581 (2005-12-01)
Ischemia/reperfusion (I/R) injury is a major cause of acute renal failure (ARF). ARF is reversible, due to an innate regenerative process, which is thought to depend partly on bone marrow-derived progenitor cells. The significance of these cells in the repair

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