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Merck

SAB4200718

Sigma-Aldrich

Anti-Elastin antibody, Mouse monoclonal

clone BA-4, purified from hybridoma cell culture

Synonym(e):

Anti-ELN, Anti-Tropoelastin

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

mouse

Antikörperform

purified from hybridoma cell culture

Antikörper-Produkttyp

primary antibodies

Klon

BA-4, monoclonal

Form

buffered aqueous solution

Speziesreaktivität

sheep, hamster, bovine, goat, frog, rabbit, porcine, human, guinea pig, canine

Konzentration

~1.0 mg/mL

Methode(n)

immunoblotting: suitable
immunohistochemistry: 10-20 μg/mL using enzyme-retrieved formalin-fixed, paraffin-embedded sheep arterial tissue sections
immunoprecipitation (IP): suitable

Isotyp

IgG1

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... EMILIN3(2006)

Allgemeine Beschreibung

Anti-Elastin antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the BA-4 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with bovine alpha-Elastin.

Immunogen

bovine alpha-Elastin

Anwendung

Anti-Elastin antibody, Mouse monoclonal has been used in:
  • immunohistochemistry
  • immunoblot
  • immunoprecipitation

Biochem./physiol. Wirkung

Elastin (ELN) provides elasticity and is integrated with other proteins from the ECM in elastic fibrils. Elastin undergoes changes of morphology with aging and at many disease states. In addition, several heritable diseases, such as supravalvular aortic stenosis, cutis laxa, Marfan syndrome, pseudoxanthoma elasticum and Buschke-Ollendorf syndrome, may result from molecular defects of elastin.

Physikalische Form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Elastin
Biochemistry of Collagens, Laminins and Elastin, 197-201 (2016)
Elastic fibres in health and disease
Baldwin AK, et al.
Expert Reviews in Molecular Medicine, 15 (2013)
Impaired elastogenesis in Hurler disease: dermatan sulfate accumulation linked to deficiency in elastin-binding protein and elastic fiber assembly
Hinek A and Wilson SE
The American Journal of Pathology, 156(3), 925-938 (2000)
Elastogenesis in human arterial disease: a role for macrophages in disordered elastin synthesis.
Krettek A, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 23(4), 582-587 (2003)

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