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Merck

SAB2501087

Sigma-Aldrich

Anti-Uncoupling Protein 2/UCP2 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-SLC25A8, Anti-UCPH, Anti-Uncoupling protein 2

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

goat

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

mouse, rat

Methode(n)

immunofluorescence: suitable
indirect ELISA: suitable
western blot: suitable

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... UCP2(7351)

Verwandte Kategorien

Allgemeine Beschreibung

Uncoupling protein 2 (UCP2) is an inner mitochondrial membrane protein. It expressed in various regions of the brain. In non-human primates, it is present in the hypothalamic nuclei, pituitary gland, brainstem, ventral tegmental area and substantia nigra. It is located on human chromosome 11q13.

Immunogen

Peptide with sequence C-DSVKQFYTKGSEH from the internal region of the protein sequence according to NP_003346.2.

Anwendung

Anti-uncoupling protein 2/UCP2 antibody has been used in immunoblotting.

Biochem./physiol. Wirkung

Uncoupling protein 2 (UCP2) controls energy metabolism and decreases the production of reactive oxygen species and guards against reperfusion damage. It plays a vital role in uncoupling electron transport from adenosine triphosphate (ATP) formation.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Physical exercise improves brain cortex and cerebellum mitochondrial bioenergetics and alters apoptotic, dynamic and auto (mito) phagy markers
Marques A I, et al.
Neuroscience, 301(8), 480-495 (2015)
The UCP2-866G/A Polymorphism Could be Considered as a Genetic Marker of Different Functional Prognosis in Ischemic Stroke After Recanalization
Cicuendez I D M, et al.
Neuromolecular Medicine, 19(4), 571-578 (2017)
Uncoupling protein 2 region on chromosome 11q13 is not linked to markers of obesity in familial type 2 diabetes
Elbein S C, et al.
Diabetes, 46(12), 2105-2108 (1997)
Jelena Stevanović-Silva et al.
Metabolism: clinical and experimental, 116, 154704-154704 (2021-01-10)
Maternal high-caloric nutrition and related gestational diabetes mellitus (GDM) are associated with a high-risk for developing metabolic complications later in life and in their offspring. In contrast, exercise is recognized as a non-pharmacological strategy against metabolic dysfunctions associated to lifestyle
Uncoupling protein 2 haplotype does not affect human brain structure and function in a sample of community-dwelling older adults
Heise, et al.
PLoS ONE, 12(8), e0181392-e0181392 (2017)

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