SAB1300696

Anti-OIT3(L) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-LZP, Anti-Liver-specific zona pellucida domain-containing protein, Anti-OIT3, Anti-Oncoprotein-induced transcript 3 protein [Precursor]
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Methode(n): indirect ELISA: 1:1000; western blot: 1:100-1:500
• NCBI-Hinterlegungsnummer: NP_689848
• UniProt-Hinterlegungsnummer: Q8WWZ8
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... OIT3(170392)

Beschreibung

Allgemeine Beschreibung

Liver-specific ZP domain-containing protein (OIT3) is a liver-specific protein involved possibly in hepatocellular function and development. Oncoprotein induced transcript 3 (OIT3) is also known as liver-specific zona pellucida domain-containing protein and is composed of 545 amino acid residues. It is expressed in the liver and secreted into the blood. OIT3 possesses a D8C (domain with conserved eight cysteines) domain, an amino-terminal signal peptide and three epidermal growth factor (EGF)-like domains. The cDNA of the protein consists of 2,255bp. The gene encoding OIT3 is localized on human chromosome 10q21.3, spans 40kb and has nine exons.

Immunogen

OIT3 (NP_689848, )
This antibody is generated from rabbits immunized with a GST tag human OIT3 recombinant protein.

Biochem./physiol. Wirkung

Oncoprotein induced transcript 3 (OIT3) may have a role in liver development and function. It has been shown to be downregulated in hepatocellular carcinoma.

Physikalische Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable